Ultra-Strong Optomechanics Incorporating the Dynamical Casimir Effect

We propose a superconducting circuit comprising a dc-SQUID with mechanically compliant arm embedded in a coplanar microwave cavity that realizes an optomechanical system with a degenerate or non-degenerate parametric interaction generated via the dynamical Casimir effect. For experimentally feasible parameters, this setup is capable of reaching the single-photon, ultra-strong coupling regime, while simultaneously possessing a parametric coupling strength approaching the renormalized cavity frequency. This opens up the possibility of observing the interplay between these two fundamental nonlinearities at the single-photon level.Comment: 7 pages, 1 figure, 1 tabl

Intermediate-mass black holes in dwarf galaxies out to redshift ∼\sim 2.4 in the Chandra COSMOS Legacy Survey

We present a sample of 40 AGN in dwarf galaxies at redshifts $z \lesssim$ 2.4. The galaxies are drawn from the \textit{Chandra} COSMOS-Legacy survey as having stellar masses $10^{7}\leq M_{*}\leq3 \times 10^{9}$ M$_{\odot}$. Most of the dwarf galaxies are star-forming. After removing the contribution from star formation to the X-ray emission, the AGN luminosities of the 40 dwarf galaxies are in the range $L_\mathrm{0.5-10 keV} \sim10^{39} - 10^{44}$ erg s$^{-1}$. With 12 sources at $z > 0.5$, our sample constitutes the highest-redshift discovery of AGN in dwarf galaxies. The record-holder is cid\_1192, at $z = 2.39$ and with $L_\mathrm{0.5-10 keV} \sim 10^{44}$ erg s$^{-1}$. One of the dwarf galaxies has $M_\mathrm{*} = 6.6 \times 10^{7}$ M$_{\odot}$ and is the least massive galaxy found so far to host an AGN. All the AGN are of type 2 and consistent with hosting intermediate-mass black holes (BHs) with masses $\sim 10^{4} - 10^{5}$ M$_{\odot}$ and typical Eddington ratios $> 1\%$. We also study the evolution, corrected for completeness, of AGN fraction with stellar mass, X-ray luminosity, and redshift in dwarf galaxies out to $z$ = 0.7. We find that the AGN fraction for $10^{9}< M_{*}\leq3 \times 10^{9}$ M$_{\odot}$ and $L_\mathrm{X} \sim 10^{41}-10^{42}$ erg s$^{-1}$ is $\sim$0.4\% for $z \leq$ 0.3 and that it decreases with X-ray luminosity and decreasing stellar mass. Unlike massive galaxies, the AGN fraction seems to decrease with redshift, suggesting that AGN in dwarf galaxies evolve differently than those in high-mass galaxies. Mindful of potential caveats, the results seem to favor a direct collapse formation mechanism for the seed BHs in the early Universe.Comment: 16 pages, 10 figures, accepted for publication in MNRA

Suboptimal Larval Habitats Modulate Oviposition of the Malaria Vector Mosquito Anopheles coluzzii.

Selection of oviposition sites by gravid females is a critical behavioral step in the reproductive cycle of Anopheles coluzzii, which is one of the principal Afrotropical malaria vector mosquitoes. Several studies suggest this decision is mediated by semiochemicals associated with potential oviposition sites. To better understand the chemosensory basis of this behavior and identify compounds that can modulate oviposition, we examined the generally held hypothesis that suboptimal larval habitats give rise to semiochemicals that negatively influence the oviposition preference of gravid females. Dual-choice bioassays indicated that oviposition sites conditioned in this manner do indeed foster significant and concentration dependent aversive effects on the oviposition site selection of gravid females. Headspace analyses derived from aversive habitats consistently noted the presence of dimethyl disulfide (DMDS), dimethyl trisulfide (DMTS) and 6-methyl-5-hepten-2-one (sulcatone) each of which unitarily affected An. coluzzii oviposition preference. Electrophysiological assays across the antennae, maxillary palp, and labellum of gravid An. coluzzii revealed differential responses to these semiochemicals. Taken together, these findings validate the hypothesis in question and suggest that suboptimal environments for An. coluzzii larval development results in the release of DMDS, DMTS and sulcatone that impact the response valence of gravid females

More, More, More: Reducing Thrombosis in Acute Coronary Syndromes Beyond Dual Antiplatelet Therapy-Current Data and Future Directions.

© 2018 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.Common to the pathogenesis of acute coronary syndromes (ACS) is the formation of arterial thrombus, which results from platelet activation and triggering of the coagulation cascade.1 To attenuate the risk of future thrombotic events, patients with ACS are treated with dual antiplatelet therapy (DAPT), namely, the combination of aspirin with a P2Y12 inhibitor, such as clopidogrel, ticagrelor, or prasugrel. Despite DAPT, some ≈10% of ACS patients experience recurrent major adverse cardiovascular events over the subsequent 30 days,2 driving the quest for more effective inhibition of thrombotic pathways. In this review, we provide an overview of studies to date and those ongoing that aim to deliver more effective combinations of antithrombotic agents to patients with recent ACS. We have chosen to confine the review to ACS patients without atrial fibrillation because those with atrial fibrillation have a clear indication for combination therapy that includes oral anticoagulation and should, we feel, be treated as a separate cohort. In this article, we discuss the limitations of the currently available clinical trial data and future directions, with suggestions for how practice might change to reduce the risk of coronary thrombosis in those at greatest risk, with minimal impact on bleeding.Peer reviewedFinal Published versio

Covariant Helicity-Coupling Amplitudes: A New Formulation

We have worked out covariant amplitudes for any two-body decay of a resonance with an arbitrary non-zero mass, which involves arbitrary integer spins in the initial and the final states. One key new ingredient for this work is the application of the total intrinsic spin operator $\vec S$ which is given directly in terms of the generators of the Poincar\'e group. Using the results of this study, we show how to explore the Lorentz factors which appear naturally, if the momentum-space wave functions are used to form the covariant decay amplitudes. We have devised a method of constructing our covariant decay amplitudes, such that they lead to the Zemach amplitudes when the Lorentz factors are set one

Ferromagnetic resonance imaging of Co films using magnetic resonance force microscopy

Lateral one-dimensional imaging of cobalt (Co) films by means of microscopic ferromagnetic resonance (FMR) detected using the magnetic resonance force microscope (MRFM) is demonstrated. A novel approach involving scanning a localized magnetic probe is shown to enable FMR imaging in spite of the broad resonance linewidth. We introduce a spatially selective local field by means of a small, magnetically polarized spherical crystallite of yttrium iron garnet (YIG). Using MRFM-detected FMR signals from a sample consisting of two Co films, we can resolve the ∼20 μm lateral separation between the films. The results can be qualitatively understood by consideration of the calculated spatial profiles of the magnetic field generated by the YIG sphere

Parametric Amplification and Back-Action Noise Squeezing by a Qubit-Coupled Nanoresonator

We demonstrate the parametric amplification and noise squeezing of nanomechanical motion utilizing dispersive coupling to a Cooper-pair box qubit. By modulating the qubit bias and resulting mechanical resonance shift, we achieve gain of 30 dB and noise squeezing of 4 dB. This qubit-mediated effect is 3000 times more effective than that resulting from the weak nonlinearity of capacitance to a nearby electrode. This technique may be used to prepare nanomechanical squeezed states

System and Method for Dynamic Aeroelastic Control

The present invention proposes a hardware and software architecture for dynamic modal structural monitoring that uses a robust modal filter to monitor a potentially very large-scale array of sensors in real time, and tolerant of asymmetric sensor noise and sensor failures, to achieve aircraft performance optimization such as minimizing aircraft flutter, drag and maximizing fuel efficiency

MSX versus IRAS Two-Color Diagrams and the CSE-Sequence of Oxygen-Rich Late-Type Stars

We present MSX two-color diagrams that can be used to characterize circumstellar environments of sources with good quality MSX colors in terms of IRAS color regions for oxygen-rich stars. With these diagrams we aim to provide a new tool that can be used to study circumstellar environments and to improve detection rates for targeted surveys for circumstellar maser emission similar to the IRAS two-color diagram. This new tool is especially useful for regions in the sky where IRAS was confused, in particular in the Galactic plane and bulge region. Unfortunately, using MSX colors alone does not allow to distinguish between carbon-rich and oxygen-rich objects. An application of this tool on 86 GHz SiO masers shows that for this type of masers an instantaneous detection rate of 60% to 80% can be achieved if target sources are selected according to MSX color (region). Our investigations may have revealed an error in the MSX point source catalog version 2.3. That is, the photometry of the 21.3 $\mu$m (MSX E filter) band for most weak 8.28 $\mu$m (or MSX A filter) band sources seems off by about a factor two (0.5--1 magnitude too bright).Comment: accepted to Astrophysical Journal, 11 pages, 11 figs of which 1 in colo

Drone Cage Design and Implementation to Enable Small Drone Architecture Testing

Geometric mechanics is a dynamical formalism that allows for simultaneous treatment of rotational and translational motion without the drawbacks of attitude parameterization sets. While geometric mechanics is well suited to deal with full six degree-of-freedom motion or significant position-attitude coupling, this formalism has yet to be extensively applied to hardware systems. The broader research goals of this work aim to prove the practical viability of this theoretical framework by applying it to a class of Crazyflie drones, which are frequently used to assess Guidance, Navigation, and Control schemes. To efficiently achieve these goals, a reliable, collapsible drone cage is required to conduct such experiments in. As a result, the team has designed and constructed a modular cage that can be used to safely test drone behavior. Requirements from the drones’ suite of hardware necessitate a cage with dimensions of 3m × 3m × 7m, a fact which drove the collapsible nature of the design. Given the cage’s modularity, its size can be further scaled for future experiments. The work here discusses the construction and development methodology of the cage, and preliminary results for a path-tracking simulation illustrate how the cage and Crazyflie hardware interface provide accurate truth-data